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"Methodology for adaptation of the ASH Guidelines for Management of Venous Thromboembolism for the Latin American context. Blood Adv. "

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"Background: From 2017 to 2020, the American Society of Hematology (ASH) collaborated with 12 hematology societies in Latin America to adapt the ASH guidelines on venous thromboembolism (VTE).

Investigación y educación

Multinational prospective cohort study over 24 years of the risk factors for ventilator-associated pneumonia in 187 ICUs in 12 Latin American countries

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"Jimenez-Alvarez LF, Reyes LP, Alvarez-Moreno CA, Gomez K, Alarcon J, Oñate JM, Aguilar-Moreno LA, Bravo-Ojeda JS, Gutierrez-Tobar IF." 29/12/2022

Investigación y educación

Multinational Prospective Cohort Study of Mortality Risk Factors in 198 ICUs of 12 Latin American Countries over 24 Years: The Effects of Healthcare-Associated Infections. J Epidemiol Glob Health.

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"Jimenez-Alvarez LF, Reyes LP, Alvarez-Moreno CA, Gomez K, Alarcon J, Oñate JM, Aguilar-Moreno LA, Ojeda JSB, Tobar IFG." 5/10/2022

Background
The International Nosocomial Infection Control Consortium (INICC) has found a high ICU mortality rate in Latin America.                                                                                   

Investigación y educación

The impact of healthcare-associated infections on mortality in ICU: A prospective study in Asia, Africa, Eastern Europe, Latin America, and the Middle East. Am J Infect Control.

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Jiménez-Alvarez LF, Gomez-Nieto K, Aguilar-Moreno LA. 06/09/2022

Background
The International Nosocomial Infection Control Consortium has found a high ICU mortality rate. Our aim was to identify all-cause mortality risk factors in ICU-patients.

Investigación y educación

CARE-MS I, CARE-MS II, CAMMS03409, and TOPAZ investigators. Alemtuzumab outcomes by age: Post hoc analysis from the randomized CARE-MS studies over 8 years. Mult Scler Relat Disord.

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Bass AD, Arroyo R, Boster AL, Boyko AN, Eichau S, Ionete C, Limmroth V, Navas C, Pelletier D, Pozzilli C, Ravenscroft J, Sousa L, Tintoré M, Uitdehaag BMJ, Baker DP, Daizadeh N, Choudhry Z, Rog D; 24/12/2020

Background
Alemtuzumab significantly improved clinical and MRI outcomes vs. subcutaneous interferon beta-1a (SC IFNB-1a) in the CARE-MS trials (NCT00530348, NCT00548405), with sustained efficacy in 2 consecutive extensions (NCT00930553, NCT02255656 [TOPAZ]).

Investigación y educación

Measurable Residual Disease Assessment and Allogeneic Transplantation as Consolidation Therapy in Adult Acute Lymphoblastic Leukemia in Colombia. Clin Lymphoma Myeloma Leuk.

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Combariza JF, Arango M, Díaz L, et al. 14/11/2020

Abstract
Detectable minimal residual disease (MRD) after therapy for acute lymphoblastic leukemia (ALL) is the strongest predictor of hematologic relapse. The objective of the study was to assess disease-free survival (DFS) and overall survival (OS) of patients with ALL according with MRD status at the end of induction therapy in a Colombian population.

Investigación y educación

Incidence and Prognostic Significance of High-Risk Cytogenetically Abnormalities in Multiple Myeloma Patients in Colombia. Clin Lymphoma Myeloma Leuk.

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Combariza JF, Ordúz R, Agudelo C, Hernandez S, Madera AM, León G, Avila V,Bautista L, Valdés J, Camargo C, Sanchez V, Mejía F, Moreno L, Ramirez C. 26/02/2022

Investigación y educación

Peritonal carcinomatosis after minimally invasive surgery versusopen radical hysterectomy: systematic review and meta-analysis. Int J Gynecol Cancer.

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Viveros-Carreño D    5/12/2022

Objective To assess the incidence of peritoneal carcinomatosis in patients undergoing minimally invasive or open radical hysterectomy for cervical cancer. 

Conclusion Minimally invasive surgery is associated with a statistically significant higher risk of peritoneal carcinomatosis after radical hysterectomy for cervical cancer compared with open surgery.

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Investigación y educación